Publications

Antagonistic nanobodies implicate mechanism of GSDMD pore formation and potential therapeutic application

Schiffelers LDJ, Tesfamariam YM, Jenster L, Diehl S, Binder SC, Normann S, Mayr J, Pritzl S, Hagelauer E, Kopp A, Alon A, Geyer M, Ploegh HL, Schmidt FI

AlphaFold2 structures guide prospective ligand discovery

Lyu J, Kapolka N, Gumpper R, Alon A, Wang L, Jain MK, Barros-Álvarez X, Sakamoto K, Kim Y, DiBerto J, Kim K, Glenn IS, Tummino TA, Huang S, Irwin JJ, Tarkhanova OO, Moroz Y, Skiniotis G, Kruse AC, Shoichet BK, Roth BL

The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination

Gao Y, Barajas-Ornelas RDC, Amon JD, Ramírez-Guadiana FH, Alon A, Brock KP, Marks DS, Kruse AC, Rudner DZ

36(9-10): 634–646

The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

Okalang U, Mualem Bar-Ner B, Rajan KS, Friedman N, Aryal S, Egarmina K, Hope R, Khazanov N, Senderowitz H, Alon A, Fass D, Michaeli S

12(6): e0260221

Dormant spores sense amino acids through the B subunits of their germination receptors

Artzi L, Alon A, Brock KP, Green AG, Tam A, Ramírez-Guadiana FH, Marks D, Kruse A, Rudner DZ

12(1): 6842

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2

Tummino TA†, Rezelj VV†, Fischer B†, Fischer A†, O'Meara MJ, Monel B, Vallet T, White KM, Zhang Z, Alon A, Schadt H, et al.

373(6554): 541–547

COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

Malone RW, Tisdall P, Fremont-Smith P, Liu Y, Huang XP, White KM, Miorin L, Moreno E, Alon A, Delaforge E, et al.

12: 633680

cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures

Javitt G†, Grossman-Haham I†, Alon A, Resnick E, Mutsafi Y, Ilani T, Fass D

28(1): 228–238

Structural Perspectives on Sigma-1 Receptor Function

Alon A, Schmidt H, Zheng S, Kruse AC

964: 5–13

AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences

Lapidoth GD, Baran D, Pszolla GM, Norn C, Alon A, Tyka MD, Fleishman SJ

83(8): 1385–406

An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1

Grossman I, Alon A, Ilani T, Fass D

425(22): 4366–78

Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase

Limor-Waisberg K, Alon A, Mehlman T, Fass D

586(23): 4119–25

Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596

Hakim M, Ezerina D, Alon A, Vonshak O, Fass D

7(11): e50649

QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains

Alon A, Heckler EJ, Thorpe C, Fass D

584(8): 1521–1525

Human quiescin-sulfhydryl oxidase, QSOX1: probing internal redox steps by mutagenesis

Heckler EJ, Alon A, Fass D, Thorpe C

47(17): 4955–4963