The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination
Gao Y, Barajas-Ornelas RDC, Amon JD, Ramírez-Guadiana FH, Alon A, Brock KP, Marks DS, Kruse AC, Rudner DZ Genes Dev, 2022, 36(9-10): 634-646 LinkPDF
Structures of the σ2 receptor enable docking for bioactive ligand discovery Alon A†, Lyu J†, Braz JM†, Tummino TA, Craik V, O'Meara MJ, Webb CM, Radchenko DS, Moroz YS, Huang XP, Liu Y, Roth BL, Irwin JJ, Basbaum AI‡, Shoichet BK‡, Kruse AC‡ Nature, 2021, 600(7890): 759-764 LinkPDF
The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3
Okalang U, Mualem Bar-Ner B, Rajan KS, Friedman N, Aryal S, Egarmina K, Hope R, Khazanov N, Senderowitz H, Alon A, Fass D, Michaeli S mBio, 2021, 12(6): e0260221 LinkPDF
Dormant spores sense amino acids through the B subunits of their germination receptors
Artzi L, Alon A, Brock KP, Green AG, Tam A, Ramírez-Guadiana FH, Marks D, Kruse A, Rudner DZ Nat Commun, 2021, 12(1): 6842 LinkPDF
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
Tummino TA†, Rezelj VV†, Fischer B†, Fischer A†, O'Meara MJ, Monel B, Vallet T, White KM, Zhang Z, Alon A, Schadt H, O'Donnell HR, Lyu J, Rosales R, McGovern BL, Rathnasinghe R, Jangra S, Schotsaert M, Galarneau JR, Krogan NJ, Urban L, Shokat KM, Kruse AC, García-Sastre A, Schwartz O, et al. Science, 2021, 373(6554): 541-547 LinkPDF
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms
Malone RW, Tisdall P, Fremont-Smith P, Liu Y, Huang XP, White KM, Miorin L, Moreno E, Alon A, Delaforge E, Hennecker CD, Wang G, Pottel J, Blair RV, Roy CJ, Smith N, Hall JM, Tomera KM, Shapiro G, Mittermaier A, Kruse AC, García-Sastre A, Roth BL, Glasspool-Malone J, Ricke DO Front Pharmacol, 2021, 12: 633680 LinkPDF
cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures
Javitt G†, Grossman-Haham I†, Alon A, Resnick E, Mutsafi Y, Ilani T, Fass D Protein Sci, 2019, 28(1): 228-238 LinkPDF
Identification of the gene that codes for the σ2 receptor Alon A†, Schmidt HR†, Wood MD†, Sahn JJ, Martin SF, Kruse AC Proc Natl Acad Sci U S A, 2017, 114(27): 7160-7165 LinkPDF
Structural Perspectives on Sigma-1 Receptor Function Alon A, Schmidt H, Zheng S, Kruse AC Adv Exp Med Biol, 2017, 964: 5-13 Link
AbDesign: An algorithm for combinatorial backbone design guided by natural conformations and sequences
Lapidoth GD, Baran D, Pszolla GM, Norn C, Alon A, Tyka MD, Fleishman SJ Proteins, 2015, 83(8): 1385-406 LinkPDF
An inhibitory antibody blocks the first step in the dithiol/disulfide relay mechanism of the enzyme QSOX1
Grossman I, Alon A, Ilani T, Fass D J Mol Biol, 2013, 425(22): 4366-78 LinkPDF
A secreted disulfide catalyst controls extracellular matrix composition and function
Ilani T, Alon A, Grossman I, Horowitz B, Kartvelishvily E, Cohen SR, Fass D Science, 2013, 341(6141): 74-6 LinkPDF
Phylogenetics and enzymology of plant quiescin sulfhydryl oxidase
Limor-Waisberg K, Alon A, Mehlman T, Fass D FEBS Lett, 2012, 586(23): 4119-25 LinkPDF
Exploring ORFan domains in giant viruses: structure of mimivirus sulfhydryl oxidase R596
Hakim M, Ezerina D, Alon A, Vonshak O, Fass D PLoS One, 2012, 7(11): e50649 LinkPDF
The dynamic disulphide relay of quiescin sulphydryl oxidase Alon A, Grossman I, Gat Y, Kodali VK, DiMaio F, Mehlman T, Haran G, Baker D, Thorpe C, Fass D Nature, 2012, 488(7411): 414-8 LinkPDF
Improved molecular replacement by density- and energy-guided protein structure optimization
DiMaio F, Terwilliger TC, Read RJ, Wlodawer A, Oberdorfer G, Wagner U, Valkov E, Alon A, Fass D, Axelrod HL, Das D, Vorobiev SM, Iwaï H, Pokkuluri PR, Baker D Nature, 2011, 473(7348): 540-3 LinkPDF
QSOX contains a pseudo-dimer of functional and degenerate sulfhydryl oxidase domains Alon A, Heckler EJ, Thorpe C, Fass D FEBS Lett, 2010, 584(8): 1521-5 LinkPDF
Human quiescin-sulfhydryl oxidase, QSOX1: probing internal redox steps by mutagenesis
Heckler EJ, Alon A, Fass D, Thorpe C Biochemistry, 2008, 47(17): 4955-63 LinkPDF
